Washington: Democrat Barack Obama has opened a six-point lead over Republican rival John McCain in the US presidential race, according to a Reuters/C-SPAN/Zogby poll released on Sunday.

Obama leads McCain by 49 per cent to 43 per cent among likely US voters in the latest four-day tracking poll, his widest lead since the poll was started on Tuesday. It was up from a four-point lead on Saturday. The poll has a margin of error of 2.9 percentage points.

Pollster John Zogby said Obama's lead was now statistically significant.

"As we watch each day, it is clear that he has gone from a two-point lead to a three-point lead on up to six points," Zogby said. "It is certainly trending his way."

Crucial group

With just over three weeks to go before the November 4 election, the poll showed Obama gaining traction among independent voters who now back him by a 21-point margin.

Among women, another crucial group, the Illinois senator held a solid 12-point lead, while the two candidates were tied among male voters at 45 per cent apiece.

Obama has widened his lead as weeks of economic turmoil shook financial markets, causing stock markets to plunge and fuelling voter concern over pocketbook issues.

Young voters aged 18 to 29 backed Obama by a 20-point margin, and he also held a double-digit lead among those who reported they had registered to vote in the past six months.

McCain had a 10-point lead among white voters, while Obama, who would be the first black US president, won the support of 92 per cent of black voters, one of the Democratic Party's most loyal constituencies.

Zogby said McCain, a former Navy pilot and Vietnam prisoner of war, appeared to be failing to connect with many voters on the issue of the economy, and a wave of attacks levelled against Obama by the McCain campaign also fell flat.

"Clearly the negative campaigning isn't working," Zogby said, noting that Obama was winning support among some voters in even the strongest traditional Republican voting blocs.

"He's getting 19 per cent support among conservatives and 35 support among born-again or evangelical [Christian] voters, which is pretty substantial," he said.